Unique "matrix" menu - who can help me create this?

I want to create a matrix menu like this

Is there anyone here who can help me put this together?

Here is how it functions:
When a user arrives, by default one of the boxes on the left and one on the top are pre-selected and display the filtered results in the middle. The idea is that a Selection on the left and a selection on the top filter the results so that the results display in the middle.

I have no idea how to create this

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