Adaptive/ Responsive Design ( difference between 15inch and 27inch)

Well i have an problem with responsive design ( different monitor sizes)

first of all i know how to optimize for an phone or an tablet with the Costumize / Hide during Breakpoint option.

My problem is the difference between a large size Monitor and a medium size Monitor and everything between.
The two screenshots should show my problem, one screenshot is taken with an 15 inch laptop( the pictures fit with the edges) the second screenshot with an 27 inch Monitor (pictures doesnt fit anymore).

Maybe you can help me.

Nicolas

PS. Hiding something on the large monitor isnt an solution for me. As example a stretched version would be.

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